- 姓名: 张磊
- 性别: 男
- 职称: 研究员
- 职务:
- 学历: 博士
- 电话: 027-87199105
- 传真:
- 电子邮件: leizhang@apm.ac.cn
- 所属部门: 磁共振影像研究部
- 通讯地址: 湖北省武汉市洪山区中国科学院精密测量与技术创新研究院波谱楼2002
学习经历
2007年09月-2011年06月 四川大学 学士2012年09月-2017年08月 美国德克萨斯大学达拉斯分校 博士工作经历2018年01月-2021年08月 中国科学院长春应用化学研究所 副研究员2021年08月-至今 中国科学院精密测量与技术创新研究院 研究员
简 历:
社会任职:
小分子磁共振造影剂的研发及活体应用
研究方向:
承担科研项目情况:
1) Haonan He, Long Xiao, Kelu Zhao, Yi Zhang, Yi Cheng, Shizhen Chen, Lei Zhang,* Xin Zhou* and Kai Liu*, Hongjie Zhang. Detection and chiral recognition of α‐hydroxyl acid through proton and CEST NMR using Yb macrocyclic complex. Angew Chem Int Edit. 2019., 58,18286 –18289
2) Lei Zhang? , André F. Martins? , Piyu Zhao, Michael Tieu, David Esteban-Gómez, Gregory T. McCandless, Carlos Platas-Iglesias and A. Dean Sherry*. Enantiomeric recognition of D- and L-lactate by CEST with the aid of a paramagnetic shift reagent. J Am Chem Soc 2017, 139(48): 17431~174373) Lei Zhang? , André F. Martins? , Piyu Zhao, Yunkou Wu, Gyula Tircso, Dean Sherry*. Lanthanide-based T2ex and CEST complexes provide new insights into the design of pH sensitive MRI agents. Angew Chem Int Edit. 2017.12.4, 56(52): 16626~166304) Lei Zhang? , André F. Martins? , Yuyan Mai, Piyu Zhao, Alexander Funk, M. Veronica Clavijo Jordan, Shanrong Zhang, Wei Chen, Yunkou Wu and A. Dean Sherry*. Imaging extracellular lactate in vitro and in vivo using CEST MRI and a paramagnetic shift reagent. Chem-Eur J, 2017, 23 (8), 1752.5) Lei Zhang*; Jingjing Li; Kai Liu*, Recent advances in gadolinium-based MRI metal responsive agent, SCI China Technol SC, 2018.7.13, 61(9): 1329~13336) Yi Zhang, Kelu Zhao, Haonan He, Sikang Wan, Andre F. Martins, Lei Zhang*and Kai Liu. A T2ex MRI Dy-based contrast agent for direct pH imaging using a ratiometric approach. Dalton Trans.2021,50, 2014-20177) Sikang Wan, Fengzhi Cui, Bo Li, Kelu Zhao, Haonan He, Yi Zhang, Jianhua Liu, Lei Zhang*, and Kai Liu*. Dysprosium-Modified Gold Nanoparticles as T2ex Contrast Agents for Magnetic Resonance Imaging. ACS Appl. Nano Mater. 2020, 3, 9, 9433–94398) Yibin Yu, Yi Cheng, Junye Tong, Lei Zhang*, Yen Wei, Mei Tian. Recent advances in thermo-sensitive hydrogels for drug delivery. J. Mater. Chem. B, 2021,9, 2979-29929) Yang Liu, Wenyao Zhen, Yinghui Wang, Jianhua Liu, Longhai Jin, Tianqi Zhang, Songtao Zhang, Ying Zhao, Na Yin, Rui Niu, Shuyan Song, Lei Zhang, and Hongjie Zhang. Double Switch Biodegradable Porous Hollow Trinickel Monophosphide Nanospheres for Multimodal Imaging Guided Photothermal Therapy Nano Lett.2019, 198, 5093-510110) Chao Ma, Jing Sun, Bo Li, Yang Feng, Yao Sun, Li Xiang, Baiheng Wu, Lingling Xiao, Baimei Liu, Vladislav S. Petrovskii, Bin Liu, Jinrui Zhang, Zili Wang, Hongyan Li, Lei Zhang, Jingjing Li, Fan Wang, Robert G?stl, Igor I. Potemkin, Dong Chen, Hongbo Zeng, Hongjie Zhang, Kai Liu & Andreas Herrmann. Nat Commun .(2021) 12:3613
代表论著:
专利申请:
2022年入选武汉英才计划
人才队伍